Table 4 The hematological parameters of TH-treated groups compared to controls
| Â | Groups | Â | ||||
|---|---|---|---|---|---|---|
| Â | 0 Normal control | 1 -ve control | 2 (0.2Â g/kg TH) | 3 (1.0Â g/kg TH) | 4 (2.0Â g/kg TH) | p valuea |
RBC (1012/L) | 7.15 (0.27) | 6.35 (0.75) | 7.35 (1.22) | 7.4 (1.025) | 6.85 (1.67) | 0.088 |
Hb (g/dl) | 15.35 (0.62) | 14.1 (1.62) | 14.8 (1.92) | 15 (1.97) | 15.25 (2.77) | 0.062 |
PCV (%) | 48 (2.5) | 42 (3.25) | 48.5 (5) | 48.5 (9) | 47.5 (8.75) | 0.047 |
MCV (fl) | 65.5 (1.5) | 66 (4.75) | 65.5 (6.75) | 66 (1.75) | 65.5 (3.75) | 0.004 |
MCH (pg) | 21 (2) | 21.5 (1.5) | 20.5 (2.25) | 21 (2.25) | 21.5 (2) | 0.958 |
MCHC (g/L) | 32.5 (1) | 31.5 (1.75) | 31 (1.5) | 31 (2.5) | 32 (3) | 0.000 |
RDW (%) | 11.85 (1.7) | 13.85 (1.7) | 12.25 (2.725) | 12.6 (1.5) | 12.9 (2.22) | 0.010 |
TWBC (109/L) | 4.85 (1.75) | 6.14 (8.72) | 5.05 (2.4) | 4.95 (6) | 6.25 (5.7) | 0.178 |
Polymorphs (%) | 33 (9.5) | 42 (19.75) | 34 (16.5) | 32 (12) | 32.5 (13.5) | 0.009 |
Lymphocytes (%) | 66 (5.5) | 54 (20.75) | 65 (13.5) | 64.5 (13.5) | 66.5 (15) | 0.010 |
Monocytes (%) | 1.5 (1.5) | 1.5 (2.5) | 1.25 (1) | 1 (0) | 1 (2) | 0.649 |
Eosinophils (%) | 0 (1.25) | 0 (1.25) | 0 | 0 (2) | 0.5 (1) | 0.534 |
Basophils (%) | 0 | 0 | 0 | 0 | 0 | 1.000 |
Platelets’ (109/L) | 809.5 (149) | 627.5 (196.75) | 734 (197) | 758.5 (178) | 710 (89.5) | 0.042 |