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Table 3 Representative tumor metastasis and proportion of mice with metastasis in CL-6 xenografted nude mice treated with K. galanga Linn. extract and control (untreated and 5-FU) groups

From: Anticholangiocarcinoma activity and toxicity of the Kaempferia galanga Linn. Rhizome ethanolic extract

Treatment group

Time at autopsy (weeks)

Lung metastasis

Macrometastasis

Proportion of mice without metastasis

Low dose K. galanga Linn. extract (100 mg/kg body weight)

3–9

0/6 (0%)

Medium dose K. galanga Linn. extract (500 mg/kg body weight)

5–9

1/6 (16.7%)

High dose K. galanga Linn. extract (1000 mg/kg body weight)

7–10

2/6 (33.3%)

Untreated control

6–7

0/6 (0%)

5-FU treated (40 mg/kg body weight)

7–9

1/6 (16.7%)