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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice

Fig. 5

Effects of YKS and KST on ISO-induced down-regulated CaMKII and CREB phosphorylation in the hippocampus. a Experiments were conducted after completing the fear conditioning test. Each animal was decapitated, and the hippocampi were dissected out for neurochemical studies. Typical photos indicate the levels of the phosphorylated form of CaMKII and CREB in the hippocampus obtained from GH and ISO treated with water or YKS and KST. The two columns of samples for each group are biological replicates. b Quantitative comparisons of the levels of each protein in the hippocampus. Each data column represents the mean ± S.E.M. obtained from 4 brain samples. *P < 0.05 vs. the GH group. #P < 0.05, ##P < 0.01 vs. the saline-treated ISO group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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