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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice

Fig. 4

The effect of YKS and KST on ISO-induced long-term fear memory deficits in mice. The Freezing time of contextual experimental condition was recorded in the therapeutic (a) and preventive/delaying procedures (b). YKS and KST were administered orally at doses of 1523.6 and 2031.8 mg/kg/day for 5–6 weeks before the test. The number of each group is 22 (GH-water), 23 (ISO-water), 12 (ISO-YKS) and 12 (ISO-KST) in (a), and 11, 11, 12 and 11 in (b). Each data column represents the mean ± S.E.M. *P < 0.05 vs. the GH group. # p < 0.05 compared with the water-administered ISO group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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