Fig. 3From: Anti-Hyperuricemic, Anti-Inflammatory and Analgesic Effects of Siegesbeckia orientalis L. Resulting from the Fraction with High Phenolic ContentAdministration of the BuOH fraction (BuOH fr.) or indomethacin after the treatment with carrageenan significantly reversed mechanical hyperalgesia in rats. Paw withdrawal thresholds were measured before (predose) and at intervals of 1, 3, and 5 h after the carrageenan injection (a). Percentage of reversal of hyperalgesia measured 3 h after the vehicle or drug administration (b). Values are displayed as mean ± SEM from 8 animals per group. * p < 0.05, and ** p < 0.01 compared with vehicleBack to article page