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Fig. 9 | BMC Complementary and Alternative Medicine

Fig. 9

From: β-Cell protection and antidiabetic activities of Crassocephalum crepidioides (Asteraceae) Benth. S. Moore extract against alloxan-induced oxidative stress via regulation of apoptosis and reactive oxygen species (ROS)

Fig. 9

Histopathological examination under microscopy: (a) Normal cellular population in the islets of langerhans in pancreas of vehicle-treated rats. b Extensive damage to the islets of langerhans and reduced dimensions of islets in diabetic control rats. (c, d) The partial restoration of normal cellular population and enlarged size of β-cells were shown by the extracts (150 mg/kg and 300 mg/kg), respectively. e The β-cell regeneration rate was determined by calculating the percentage of H & E positive cells over the total number of cells. Values were represented as mean ± SD. ## p < 0.01 as compared with the control group; *p < 0.05 and **p < 0.01 as compared with the alloxan control group

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