Treatment | Dose (mg/kg, p.o) | Onset of diarrhea (min) | Total # of feces | Total # of wet feces | Total weight of feces (gm) | Total weight of wet feces (gm) | % Inhibition of defecation |
---|---|---|---|---|---|---|---|
Control | - | 13.17 ± 1.08 | 9.67 ± 0.33 | 6.67 ± 0.33 | 0.46 ± 0.01 | 0.39 ± 0.009 | – |
Loperamide | 3 | 93.33 ± 2.40a3c3d3e3 | 3.5 ± 0.22a3c3e1 | 1.5 ± 0.22a3c2 | 0.13 ± 0.008a3c3d3 | 0.08 ± 0.007a3c3 | 77.5 |
ASLC | 100 | 35.67 ± 1.50a3d3e3 | 6.83 ± 0.31a3d3e3 | 3.17 ± 0.31a3d2e3 | 0.34 ± 0.016a3d3e3 | 0.24 ± 0.022a3d3e3 | 52.4 |
ASLC | 200 | 68.33 ± 2.09a3e3 | 4.50 ± 0.22a3e3 | 1.67 ± 0.21a3 | 0.22 ± 0.015a3e3 | 0.14 ± 0.017a3e3 | 75.0 |
ASLC | 400 | 185.33 ± 3.72a3 | 2.33 ± 0.21a3 | 0.83 ± 0.17a3 | 0.08 ± 0.007a3 | 0.04 ± 0.008a3 | 87.6 |