Skip to main content

Table 1 Effect of the aqueous stem extract of L. camara on castor oil induced diarrhea in mice

From: Evaluation of the anti-diarrheal activity of the aqueous stem extract of Lantana camara Linn (Verbenaceae) in mice

Treatment

Dose (mg/kg, p.o)

Onset of diarrhea (min)

Total # of feces

Total # of wet feces

Total weight of feces (gm)

Total weight of wet feces (gm)

% Inhibition of defecation

Control

-

13.17 ± 1.08

9.67 ± 0.33

6.67 ± 0.33

0.46 ± 0.01

0.39 ± 0.009

–

Loperamide

3

93.33 ± 2.40a3c3d3e3

3.5 ± 0.22a3c3e1

1.5 ± 0.22a3c2

0.13 ± 0.008a3c3d3

0.08 ± 0.007a3c3

77.5

ASLC

100

35.67 ± 1.50a3d3e3

6.83 ± 0.31a3d3e3

3.17 ± 0.31a3d2e3

0.34 ± 0.016a3d3e3

0.24 ± 0.022a3d3e3

52.4

ASLC

200

68.33 ± 2.09a3e3

4.50 ± 0.22a3e3

1.67 ± 0.21a3

0.22 ± 0.015a3e3

0.14 ± 0.017a3e3

75.0

ASLC

400

185.33 ± 3.72a3

2.33 ± 0.21a3

0.83 ± 0.17a3

0.08 ± 0.007a3

0.04 ± 0.008a3

87.6

  1. All values are expressed as mean ± standard error of the mean (SEM), (n = 6); Data was analyzed by one way ANOVA followed by Tukey post hoc test; acompared to the control, bto the standard drug, cto 100 mg/kg, dto 200 mg/kg, eto 400 mg/kg; 1 p < 0.05, 2 p < 0.01, 3 p < 0.001
  2. ASLC aqueous stem extract of L. camara. Mice in the control group received distilled water (10 ml/kg)