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Fig. 7 | BMC Complementary and Alternative Medicine

Fig. 7

From: Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

Fig. 7

Schematic model of the survival and proliferative effects of AOF extract on RSC96 Schwann cell. Stimulation of Schwann cell with AOF extract activate IGF-I signaling, leading to upregulation of the PI3K/Akt pathway and activation of the cell cycle regulatory proteins cyclin D1, E and A, resulting in the survival and proliferation of RSC96 Schwann cell

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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