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Table 2 Effects of P. pellucida aqueous extract on hematological parameters

From: Aqueous extract of Peperomia pellucida (L.) HBK accelerates fracture healing in Wistar rats

Parameters NC FC F100 mg/kg F200 mg/kg F400 mg/kg N400 mg/kg
WBCs(103/uL) 11.27 ± 1.1 14.17 ± 0.9 21.63 ± 2.0**# 22.74 ± 6.7***### 8.270 ± 1.6 12.30 ± 1.6
LYM(103/uL) 4.713 ± 0.6 5.633 ± 0.8 4.577 ± 0.3 4.550 ± 0.4 4.103 ± 1.1 6.120 ± 0.1
MID(103/uL) 1.303 ± 0.03 1.243 ± 0.5 1.230 ± 0.01 1.263 ± 0.03 1.853 ± 0.7 4.367 ± 0.1***###
GRA(103/uL) 7.767 ± 0.9 5.250 ± 0.8 5.257 ± 0.6 5.000 ± 0.9 4.017 ± 1.2* 4.267 ± 0.2*
RBCs(103/uL) 4.557 ± 0.3 5.317 ± 0.8 4.437 ± 0.4 4.467 ± 0.4 4.643 ± 0.2 5.210 ± 0.2
HCT(%) 40.40 ± 0.7 40.43 ± 1.9 40.17 ± 1.8 40.70 ± 0.3 44.77 ± 2.9 40.30 ± 0.8
MCV(fl) 88.67 ± 3.3 86.07 ± 0.6 87.47 ± 2.3 84.80 ± 0.4 96.00 ± 5.7 100.7 ± 9.9
RDW(%) 18.27 ± 2.0 21.80 ± 2.0 16.27 ± 1.6 23.30 ± 3.0 16.20 ± 2.0 15.37 ± 2.7
MCH(Pg) 37.07 ± 4.3 37.77 ± 3.0 35.43 ± 3.0 29.57 ± 3.2 40.90 ± 2.0 55.90 ± 3.2**##
MCHC(g/dl) 40.17 ± 3.5 37.30 ± 3.4 35.10 ± 5.5 39.37 ± 6.9 47.40 ± 1.7 66.40 ± 6.0**##
HGB(g/dl) 12.87 ± 0.5 12.70 ± 0.5 12.32 ± 0.8 12.40 ± 0.23 13.50 ± 0.6 12.98 ± 1.7
PLT(103/uL) 457.7 ± 81.6 439.7 ± 101.5 315.3 ± 82.1 386.3 ± 94.7 283.0 ± 10.3 327.0 ± 18.0
MPV(fl) 14.47 ± 2.1 12.20 ± 1.6 18.10 ± 1.3 11.93 ± 0.9 47.60 ± 4.9 ***### 48.27 ± 4.7***###
  1. Values represent the mean ± SEM, n = 5, *p < 0.05**, p < 0.01, *** p < 0.001: significant difference compared to NC. #p < 0.05,## p < 0.01, ### p < 0.001: significant difference compared to FC. NC Normal control rats, FC Fracture control rats. F100 mg/kg, F200 mg/kg and F400 mg/kg = Fractured rats treated with the aqueous extract of P. pellucida at the doses of 100, 200 and 400 mg/kg respectively, N400 mg/kg = Normal rats treated with P. pellucida at the dose of 400 mg/kg. WBCs White blood cells, LYM Lymphocytes, MID Minimum inhibition dilution, GRA Granulocytes, RBCs Red blood cells, HCT Haematocrits, MCV Mean corpuscular volume, RDW Red cell distribution width, HGB Haemoglobin, MCH Mean corpuscular haemoglobin, MCHC Mean cell haemoglobin concentration, PLT Platelets, MPV Mean platelet volume