Parameters | Test materials | |||||
---|---|---|---|---|---|---|
POL4 .Cr | Verapamil | Ci. Cr | Gs. Cr | Ns. Cr | Tfg. Cr | |
Effect against P.E (1 μM)-induced contractions | ||||||
% Vmax/Conc. (mg/ml) | 141.43 ± 4.63/1 | - | - | 221.66 ± 15.89***/1 | 131.95 ± 6.95*/0.03 | - |
Complete inhibition with resultant EC50 values with 95% confidence interval | - | 0.417 mg/ml (0.31–0.54) | 2.01 mg/ml (1.62–2.49) | - | - | 2.29 mg/ml (1.15–4.56) |
Effect against K+ (80 mM)-induced contractions | ||||||
Complete inhibition with resultant EC50 values | 4.70 mg/ml (3.94–5.60) | 0.27 mg/ml (0.18–0.39) | 0.31 mg/ml (0.19–0.52) | 3.13 mg/ml (2.15–4.56) | 0.68 mg/ml (0.41–1.14) | 1.40 mg/ml (0.91–2.15) |