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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: N-butanol extracts of Morinda citrifolia suppress advanced glycation end products (AGE)-induced inflammatory reactions in endothelial cells through its anti-oxidative properties

Fig. 2

Effects of noni extracts on RAGE (a), ICAM-1 (b), and PAI-1 (c) mRNA levels in AGE-exposed HUVECs. HUVECs were treated with 100 μg/ml AGE-BSA or non-glycated BSA in the presence or absence of 670 ng/ml n-butanol extracts of noni for 4 h. Then total RNAs were transcribed and amplified by real-time PCR. Data were normalized by the intensity of β-actin (a) or 18S mRNA-derived signals (b and c) and then related to the value obtained with non-glycated BSA treatment alone. a N = 4 per group. b and c N = 8 per group. * and **, p < 0.05 and p < 0.01 compared to the value with AGEs alone, respectively

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