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Table 2 Effect of CP1 on the oxidative stress markers in hippocampus

From: Neuroprotective and cognitive-enhancing effects of the combined extract of Cyperus rotundus and Zingiber officinale

Group

MDA (nmol/mg · protein)

SOD (unit/mg · protein)

GSH-Px (unit/mg · protein)

CAT (unit/mg · protein)

Vehicle + ACSF

0.0008 ± 0.0002###

3.3230 ± 0.1195###

0.0829 ± 0.0155

1 09.2071 ± 1.5467###

Vehicle + AF64A

0.0021 ± 0.0005***

2.1633 ± 0.1244***

0.0518 ± 0.0163

84.6617 ± 2.5905***

Donepezil + AF64A

0.0011 ± 0.0001##

2.9833 ± 0.3891##

0.0743 ± 0.0185

106.4200 ± 5.6561##

Vitamin C + AF64A

0.0011 ± 0.0001#

3.1532 ± 0.1500###

0.0870 ± 0.0095

106.8167 ± 3.6787##

CP1 100 mg/kgBW + AF64A

0.0013 ± 0.0002#

2.9210 ± 0.2465##

0.0705 ± 0.0235

101.3417 ± 6.1163#

CP1 200 mg/kgBW + AF64A

0.0011 ± 0.0001##

2.4226 ± 0.0834***

0.0624 ± 0.0096

105.8271 ± 3.6703##

CP1 300 mg/kgBW + AF64A

0.0015 ± 0.0001#

2.3510 ± 0.0531***

0.0612 ± 0.0088

102.3483 ± 5.4788##

  1. *, *** p-value < .05 and.001 respectively; compared to vehicle + ACSF group. #, ##, ### p-value < .05, .01 and .001 respectively; compared to vehcle + AF64A group)