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Table 3 Stability of AAs in rat plasma expressed as RSD% (n = 5)

From: Comparative studies on the multi-component pharmacokinetics of Aristolochiae Fructus and honey-fried Aristolochiae Fructus extracts after oral administration in rats

Compound

Concentration (ng/mL)

Freeze-thaw stability (RSD/%)

Long-term stability (RSD/%)

Short-term stability (RSD/%)

Post-preparation stability (RSD/%)

AA I

1.83

1.1

0.28

0.58

0.65

457.5

10.3

6.9

8.7

2.0

1830

12.9

7.6

6.5

4.5

AA II

8.00

1.3

1.2

5.0

4.4

400

10.2

8.2

5.5

3.6

3200

14.3

7.3

9.3

6.5

AA C

186.3

5.8

8.3

14.0

9.2

372.5

7.3

9.9

12.6

8.5

2980

12.9

12.0

13.0

7.0

AA D

36.8

4.8

5.2

5.0

4.5

460

8.4

2.5

11.7

3.1

3680

14.3

12.7

8.6

2.8

7-OH AA I

82.0

6.2

2.0

7.1

5.1

410

12.3

6.4

11.8

4.2

3280

13.4

11.1

9.1

6.7