Table 4 In vivo antidiarrheal indices of 80ME and solvent fractions of the leaves of Myrtus communis
Dose (mg/kg) | Delay in defecation (time of onset in min, Dfreq) (%) | Gut meal travel distance (Gmeq) (%) | Purging frequency in number of wet stools (%) | In vivo antidiarrheal index (ADI) |
|---|---|---|---|---|
Control | ------- | ------- | ------- | ------- |
80ME 100 | 43.04 | 33.54 | 42.58 | 39.47 |
80ME 200 | 89.12 | 46.12 | 62.52 | 63.58 |
80ME 400 | 126.72 | 62.31 | 74.96 | 83.96 |
Loperamide 3 | 110.64 | 59.61 | 72.56 | 78.22 |
Control | ------- | ------ | ------ | ----- |
CF 200 | 53.84 | 27.99 | 38.46 | 38.69 |
CF 300 | 75.25 | 35.11 | 51.23 | 51.34 |
CF 400 | 89.59 | 44.86 | 58.92 | 61.87 |
Loperamide 3 | 106.85 | 60.56 | 74.31 | 78.34 |
Control | ------ | ------ | ------ | ------ |
MF 200 | 50.48 | 21.24 | 31.07 | 32.18 |
MF 300 | 96.16 | 35.85 | 48.93 | 55.25 |
MF 400 | 124.29 | 47.54 | 62.67 | 71.81 |
Loperamide 3 | 140.63 | 61.47 | 75.56 | 86.76 |
Control | ------- | ------- | -------- | ------- |
AF 200 | 2.16 | 4.81 | 8.93 | 4.53 |
AF 300 | 11.54 | 12.58 | 15.60 | 13.13 |
AF 400 | 16.83 | 20.73 | 24.40 | 20.42 |
AF 800 | 94.24 | 38.61 | 53.33 | 57.89 |
loperamide | 140.63 | 61.47 | 75.56 | 86.76 |