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Table 3 Influence of the aqueous and methanol extracts of Piptadeniastrum africanum on organs weight after CFA induced arthritis

From: Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund’s adjuvant-induced arthritis in rats

 

Dose (mg/kg)

Liver

Spleen

Kidney

Thymus

Healthy control

-

6.69 ± 0.16

0.60 ± 0.01

0.91 ± 0.03

0.63 ± 0.04

Arthritic control

-

9.19 ± 0.29β

1.27 ± 0.04β

1.35 ± 0.08β

0.31 ± 0.01β

Indomethacin

5

7.45 ± 0.40a

0.81 ± 0.01a

0.98 ± 0.02a

0.54 ± 0.01a

Aqueous extract

200

7.85 ± 0.03

0.90 ± 0.05

1.12 ± 0.01

0.45 ± 0.04

400

6.61 ± 0.09b

0.77 ± 0.05a

0.91 ± 0.09b

0.54 ± 0.02a

Methanol extract

200

7.55 ± 0.30a

0.89 ± 0.01

1.03 ± 0.04a

0.59 ± 0.06b

400

6.55 ± 0.30c

0.74 ± 0.14b

0.93 ± 0.06b

0.62 ± 0.01b

  1. Each value represents the mean ± ESM for six animals and analyses by two-way ANOVA followed by Tukey post-hoc test, β P < 0.01 when compared to healthy control, a P < 0.05, b P < 0.01, c P < 0.001 when compared to arthritic control