Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats

Table 6 Effects of EAF from B. javanica seeds on liver and renal function markers in T2D rats

Groups	ALP(U/L)	ALT (U/L)	AST (U/L)	Urea (mmol/L)	Creatinine (μmol/L)
NDC	141.33 ± 16.11	45.50 ± 2.45	129.17 ± 8.93	6.23 ± 0.64	29.17 ± 1.01
DC	319.33 ± 10.99^a	172.67 ± 15.09^a	290.00 ± 11.55^a	18.98 ± 2.73^a	35.00 ± 2.11
D + EAF25	179.83 ± 19.83	81.17 ± 7.06^a	159.50 ± 15.72	11.22 ± 1.27	30.50 ± 3.56
D + EAF50	159.17 ± 24.03	60.67 ± 3.35	145.33 ± 15.64	9.52 ± 1.52	27.50 ± 1.12
D + GLI	146.67 ± 10.50	58.17 ± 4.52	138.83 ± 8.33	10.37 ± 1.80	29.00 ± 0.93

ALP alkaline phosphatase, ALT alanine aminotransferase, AST aspartate aminotransferase. The results are presented the mean ± SE for 6 rats in each group. NDC non-diabetic control, DC diabetic control, D + EAF25 diabetic rats treated with ethyl acetate fraction 25 mg/kg b.w., D + EAF50 diabetic rats treated with ethyl acetate fraction 50 mg/kg b.w., D + GLI diabetic rats treated with glibenclamide 10 mg/kg b.w. The results are considered significant when p < 0.05
^aCompared with NDC

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