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Table 3 Effects of EAF from B. javanica seeds on fasting blood glucose levels in T2D rats

From: Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats

Groups

Fasting blood glucose level (mmol/L)

0 Day

Day 7

Day 14

Day 21

Day 28

NDC

4.38 ± 0.28

4.47 ± 0.38

4.28 ± 0.23

4.23 ± 0.10

4.17 ± 0.12

DC

12.83 ± 0.95

13.95 ± 0.77

16.22 ± 1.19

19.33 ± 1.45

22.25 ± 1.97a

D + EAF25

13.43 ± 1.01

13.25 ± 1.09

12.13 ± 1.71

10.98 ± 1.56

9.43 ± 1.12a

D + EAF50

14.25 ± 0.93

12.65 ± 0.67

11.02 ± 0.59

8.82 ± 0.67

7.87 ± 1.15a

D + GLI

16.90 ± 1.63

17.63 ± 2.13

12.97 ± 0.72

11.83 ± 1.27

9.22 ± 0.65a

  1. The results are expressed as mean ± SE (n = 6). NDC non-diabetic control, DC diabetic control, D + EAF25 diabetic rats treated with ethyl acetate fraction 25 mg/kg b.w., D + EAF50 diabetic rats treated with ethyl acetate fraction 50 mg/kg b.w., D + GLI diabetic rats treated with glibenclamide 10 mg/kg b.w. The results are considered significant when p < 0.05
  2. aCompared with 0 day