Fig. 1From: Anti-inflammatory potential of Capparis spinosa L. in vivo in mice through inhibition of cell infiltration and cytokine gene expressionCS methanol extract decreased the CHS reaction. Mice were sensitized on the shaved ventral abdomen on days 0 and 1 by applying 50 μl of 0.5% DNFB (positive control ■), or were treated with the vehicle alone (negative control●); all groups of mice were challenged with 20 μl of 0.2% DNFB on the right ears on day 6. a Scheme for the experimental protocol. b Another group of mice was sensitized and challenged with DNFB and received i.p. injections of CS extract (▲) at a dose of 1.07 g/Kg. c Histograms representing ear swelling 48 h after challenge. d Mice received i.p. injections of either methanol (▲) or ethanol (▼) CS extracts at a dose of 1.07 g/Kg. e Mice received i.p. injections of CS methanol extract at doses of either of 1.07 g/Kg(▲) or 0.428 g/Kg body weight (▼) on days -1, 0, 1, 2, 5, 6 and 7. Data were expressed as averages of the values of ear swelling after the challenge. P value <0.05 was considered to be significant [* p < 0.05; ** p < 0.01; *** p < 0.001]. Data are representative of 3 or 2 number of experiments with n = 5 of mice per group (Except the negative control) (Additional file 1)Back to article page