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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Anti-inflammatory potential of Capparis spinosa L. in vivo in mice through inhibition of cell infiltration and cytokine gene expression

Fig. 1

CS methanol extract decreased the CHS reaction. Mice were sensitized on the shaved ventral abdomen on days 0 and 1 by applying 50 μl of 0.5% DNFB (positive control ■), or were treated with the vehicle alone (negative control); all groups of mice were challenged with 20 μl of 0.2% DNFB on the right ears on day 6. a Scheme for the experimental protocol. b Another group of mice was sensitized and challenged with DNFB and received i.p. injections of CS extract (▲) at a dose of 1.07 g/Kg. c Histograms representing ear swelling 48 h after challenge. d Mice received i.p. injections of either methanol (▲) or ethanol () CS extracts at a dose of 1.07 g/Kg. e Mice received i.p. injections of CS methanol extract at doses of either of 1.07 g/Kg(▲) or 0.428 g/Kg body weight () on days -1, 0, 1, 2, 5, 6 and 7. Data were expressed as averages of the values of ear swelling after the challenge. P value <0.05 was considered to be significant [* p < 0.05; ** p < 0.01; *** p < 0.001]. Data are representative of 3 or 2 number of experiments with n = 5 of mice per group (Except the negative control) (Additional file 1)

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