Experimental groups
|
Parameters (mg/dL)
|
---|
Bilirubin
|
Urea
|
Creatinin
|
Faecal cholesterol
|
---|
HC rats + dH2O
|
0,87 ± 0,18
|
0.47 ± 0.02
|
0.41 ± 0.02
|
5,58 ± 1,04
|
HC +4 weeks treatment
|
240 mg/kg
|
0,90 ± 0,12
|
0.31 ± 0.04*
|
0.26 ± 0.04*
|
11,47 ± 0,75*
|
320 mg/kg
|
0,89 ± 0,14
|
0.28 ± 0.05*
|
0.24 ± 0.05*
|
14,11 ± 1,6*
|
400 mg/kg
|
0,91 ± 0,15
|
0.26 ± 0.03*
|
0.22 ± 0.03*
|
15,04 ± 1,98*
|
HC + Atorvastatin
|
1 mg/kg
|
0,92 ± 0,11
|
0.27 ± 0.03
|
0.28 ± 0.03*
|
15,96 ± 1,64*
|
NC rats
|
0,94 ± 0,13
|
0.35 ± 0.03
|
0.25 ± 0.03
|
1,04 ± 0,27
|
- Data are represented as mean ± standard error of mean, n = 5. One-way ANOVA + LSD test against dH2O: distilled rats: *P < 0.05
-
HC Hypercholesterolemic rats, NC Normo-cholesterolemic rats