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Table 6 Effect of the aqueous extract of C. occidentalis on markers of oxidative stress

From: Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats

 

Experimental groups

MDA

(μM/100 g of tissue)

ROOH

(μM/100 g of tissue)

CAT

(mMH2O2/min per g of protein)

Protein

(g/100 g of tissue)

Glutathione

(mmol/L)

Liver homogenates

dH2O

10.77 ± 1.44

1.28 ± 0.10

0.02 ± 0.13

54.11 ± 0.54

---

400 mg/kg extract

8.89 ± 1.77*

0.87 ± 0.15***

0.19 ± 0.17*

29.33 ± 3.16**

---

Blood plasma

dH2O

19.67 ± 1.23

0.04 ± 0.11

---

---

0.44 ± 0,056

400 mg/kg extract

7.13 ± 1.44***

0.07 ± 0.12*

---

---

0.23 ± 0,033**

Blood pellet hemolysates

dH2O

---

---

0.01 ± 0.014

43.77 ± 4.21

---

400 mg/kg extract

---

---

0.14 ± 0.14***

52.65 ± 0.43*

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  1. CAT catalase, MDA malondialdehyde, ROOH hydroperoxide. Values are mean ± S.E.M., n = 5. ANOVA + LSD test vs. negative control: * P < 0.05, **P < 0.01, ***P < 0.001