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Table 6 Effect of the aqueous extract of C. occidentalis on markers of oxidative stress

From: Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats

  Experimental groups MDA (μM/100 g of tissue) ROOH (μM/100 g of tissue) CAT (mMH2O2/min per g of protein) Protein (g/100 g of tissue) Glutathione (mmol/L)
Liver homogenates dH2O 10.77 ± 1.44 1.28 ± 0.10 0.02 ± 0.13 54.11 ± 0.54 ---
400 mg/kg extract 8.89 ± 1.77* 0.87 ± 0.15*** 0.19 ± 0.17* 29.33 ± 3.16** ---
Blood plasma dH2O 19.67 ± 1.23 0.04 ± 0.11 --- --- 0.44 ± 0,056
400 mg/kg extract 7.13 ± 1.44*** 0.07 ± 0.12* --- --- 0.23 ± 0,033**
Blood pellet hemolysates dH2O --- --- 0.01 ± 0.014 43.77 ± 4.21 ---
400 mg/kg extract --- --- 0.14 ± 0.14*** 52.65 ± 0.43* ---
  1. CAT catalase, MDA malondialdehyde, ROOH hydroperoxide. Values are mean ± S.E.M., n = 5. ANOVA + LSD test vs. negative control: * P < 0.05, **P < 0.01, ***P < 0.001