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Table 2 Variation of the food intake during treatment

From: Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats

 

Drugs

Doses

mg/kg

1st week

(%/week)

2nd week

(%/week)

3rd week

(%/week)

4th week (%/week)

 

HC + Distilled water

0

44.66 ± 1.12%

54.12 ± 1.10%

55.11 ± 1.22%

57.87 ± 1.23%

During treatment

HC + Extract

240

56.80 ± 1.12%

54.47 ± 1.14%

50.23 ± 1.24%*a

47.47 ± 1.32%**a

320

54.23 ± 1.45%

52.39 ± 1.09%*a

50.22 ± 1.19%*a

45.39 ± 1.23%**a

400

39.55 ± 1.33%*a

35.54 ± 1.32%*a

28.34 ± 1.12%**a

23.68 ± 1.45%**a

HC + Atorvastatin

1

36.17 ± 1.32%**a

37.16 ± 1.06%**a

39.37 ± 1.32%**a

43.41 ± 1.13%**a

After treatment

HC + Extract

240

53.13 ± 1.56%

56.32 ± 1.21%*b

58.87 ± 1.22%*b

62.23 ± 1.12%**b

320

56.16 ± 1.32%*b

55.33 ± 1.41%*b

60.77 ± 1.42%*b

62.44 ± 1.54%**b

400

47.33 ± 1.22%*b

49.33 ± 1.25%**b

52.22 ± 1.32%**b

59.80 ± 1.11%**b

HC + Atorvastatin

1

39.21 ± 1.14%*b

41.89 ± 1.31%*b

45.82 ± 1.34%*b

49.15 ± 1.22%**b

  1. Values are means ± S.E.M., n = 5, *P < 0.05, **P < 0.01, HC Hypercholesterolemic rat; asignificant difference compared to HC+ Distilled water; bsignificant difference compared to animals previously treated with aqueous extract during the treatment at the same dose