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Table 1 Variation of water consumption

From: Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats

 

Drugs

Doses

mg/kg

1st week

(ml/rat/week)

2nd week

(ml/rat/week)

3rd week

(ml/rat/week)

4th week

(ml/rat/week)

 

HC + Distilled water

0

116.12 ± 1.21

137.12 ± 1.12

142.10 ± 1.22

146.21 ± 1.32

During treatment

HC + Extract

240

179.04 ± 1.23*a

158.32 ± 1.16*a

160.24 ± 1.14*a

179.31 ± 1.22*a

320

139.43 ± 1.22**a

200.31 ± 1.32**a

215.12 ± 1.32**a

236.83 ± 1.11**a

400

178.43 ± 2.33**a

239.25 ± 1.67**a

265.27 ± 2.37**a

289.66 ± 1.23**a

HC + Atorvastatin

1

145.95 ± 1.12

164.75 ± 1.13

174.15 ± 1.13

166.64 ± 1.12

After treatment

HC + Extract

240

86.33 ± 1.17**b

88.44 ± 1.17**b

89.22 ± 1.17**b

89.10 ± .1.20**b

320

95.32 ± 1.66**b

86.22 ± 1.16**b

97.12 ± 1.77**b

98.44 ± 1.25**b

400

103.93 ± 1.11**b

99.77 ± 1.11**b

100.93 ± 1.01**b

101.65 ± 0.83**b

HC + Atorvastatin

1

141.85 ± 3.72

162.75 ± 2.76

160.75 ± 3.78

166.69 ± 1.03

  1. Values are means ± S.E.M., n = 5, *P < 0.05, **P < 0.01 significant difference compared to HC+ Distilled water. HC Hypercholesterolemic rat; asignificant difference compared to HC+ Distilled water; bsignificant difference compared to animals previously treated with aqueous extract during the treatment at the same dose