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Table 4 Effects of various treatments on total proteins and prostatic acid phosphatase in castrated rats after four weeks of treatment

From: Androgenic effects of aqueous and methanolic extracts of Ficus asperifolia in male Wistar rats

Treatments Total proteins Prostatic acid phosphatase (U/g)
Epididymis (mg/g) Plasma (mg/ml)
Normal plus distilled water (10 ml/kg b.w.) 85.70 ± 8.82 61.18 ± 3.33 2.55 ± 0.63
Castrated plus distilled water (10 ml/kg b.w.) 52.03 ± 11.18 58.99 ± 3.06 0.21 ± 0.04C
Castrated plus testosterone (0.5 mg/kg b.w.) 75.68 ± 16.84 64.92 ± 1.88 0.78 ± 0.10*
5% Tween 80 (10 ml/kg b.w. plus testosterone 62.13 ± 8.90 62.15 ± 5.39 0.75 ± 0.24
Bicalutamide (2 mg/kg b.w.) plus testosterone 45.33 ± 9.22 56.10 ± 4.24 0.37 ± 0.17
Castrated plus aqueous extract
 100 mg/kg b.w. 91.84 ± 14.57 64.62 ± 3.01 0.59 ± 0.20
 500 mg/kg b.w. 77.30 ± 24.02 66.26 ± 3.10 0.28 ± 0.06
Castrated plus methanolic extract
 100 mg/kg b.w. 59.24 ± 15.86 78.18 ± 2.80*** 0.26 ± 0.08
 500 mg/kg b.w. 67.82 ± 20.63 70.27 ± 4.93* 0.54 ± 0.11
Testosterone (0.5 mg/kg b.w.) plus aqueous extract
 100 mg/kg b.w. 108.73 ± 22.76 45.27 ± 2.51### 0.51 ± 0.04
 500 mg/kg b.w. 127.87 ± 22.14# 50.93 ± 1.93## 0.58 ± 0.09
Testosterone (0.5 mg/kg b.w.) plus methanolic extract
 100 mg/kg b.w. 162.83 ± 33.53### 62.30 ± 4.87 0.35 ± 0.10
 500 mg/kg b.w. 105.20 ± 16.93 57.15 ± 1.14 0.35 ± 0.09
Bicalutamide (2 mg/kg b.w.) plus aqueous extract
 100 mg/kg b.w. 44.34 ± 10.49 70.29 ± 3.74 0.11 ± 0.05
 500 mg/kg b.w. 22.40 ± 7.55 64.24 ± 3.86 0.24 ± 0.06
Bicalutamide (2 mg/kg b.w.) plus methanolic extract
 100 mg/kg b.w. 29.62 ± 7.43 59.26 ± 2.20 0.15 ± 0.06
 500 mg/kg b.w. 26.55 ± 10.15 53.73 ± 2.50 0.18 ± 0.03
  1. All values: Mean ± SEM; Number of rats per group =5; C: p < 0.001 compared to normal rats; *: p < 0.05; ***: p < 0.001 compared to distilled water treated rats; #: p < 0.05; ##: p < 0.01; ###: p < 0.001 compared to testosterone group; : p < 0.05; : p < 0.01; : p < 0.001 compared to rats treated only with plant extracts