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Table 4 Effects of various treatments on total proteins and prostatic acid phosphatase in castrated rats after four weeks of treatment

From: Androgenic effects of aqueous and methanolic extracts of Ficus asperifolia in male Wistar rats

Treatments

Total proteins

Prostatic acid phosphatase (U/g)

Epididymis (mg/g)

Plasma (mg/ml)

Normal plus distilled water (10 ml/kg b.w.)

85.70 ± 8.82

61.18 ± 3.33

2.55 ± 0.63

Castrated plus distilled water (10 ml/kg b.w.)

52.03 ± 11.18

58.99 ± 3.06

0.21 ± 0.04C

Castrated plus testosterone (0.5 mg/kg b.w.)

75.68 ± 16.84

64.92 ± 1.88

0.78 ± 0.10*

5% Tween 80 (10 ml/kg b.w. plus testosterone

62.13 ± 8.90

62.15 ± 5.39

0.75 ± 0.24

Bicalutamide (2 mg/kg b.w.) plus testosterone

45.33 ± 9.22

56.10 ± 4.24

0.37 ± 0.17

Castrated plus aqueous extract

 100 mg/kg b.w.

91.84 ± 14.57

64.62 ± 3.01

0.59 ± 0.20

 500 mg/kg b.w.

77.30 ± 24.02

66.26 ± 3.10

0.28 ± 0.06

Castrated plus methanolic extract

 100 mg/kg b.w.

59.24 ± 15.86

78.18 ± 2.80***

0.26 ± 0.08

 500 mg/kg b.w.

67.82 ± 20.63

70.27 ± 4.93*

0.54 ± 0.11

Testosterone (0.5 mg/kg b.w.) plus aqueous extract

 100 mg/kg b.w.

108.73 ± 22.76

45.27 ± 2.51###

0.51 ± 0.04

 500 mg/kg b.w.

127.87 ± 22.14#

50.93 ± 1.93##

0.58 ± 0.09

Testosterone (0.5 mg/kg b.w.) plus methanolic extract

 100 mg/kg b.w.

162.83 ± 33.53###

62.30 ± 4.87

0.35 ± 0.10

 500 mg/kg b.w.

105.20 ± 16.93

57.15 ± 1.14

0.35 ± 0.09

Bicalutamide (2 mg/kg b.w.) plus aqueous extract

 100 mg/kg b.w.

44.34 ± 10.49

70.29 ± 3.74

0.11 ± 0.05

 500 mg/kg b.w.

22.40 ± 7.55

64.24 ± 3.86

0.24 ± 0.06

Bicalutamide (2 mg/kg b.w.) plus methanolic extract

 100 mg/kg b.w.

29.62 ± 7.43

59.26 ± 2.20

0.15 ± 0.06

 500 mg/kg b.w.

26.55 ± 10.15

53.73 ± 2.50

0.18 ± 0.03

  1. All values: Mean ± SEM; Number of rats per group =5; C: p < 0.001 compared to normal rats; *: p < 0.05; ***: p < 0.001 compared to distilled water treated rats; #: p < 0.05; ##: p < 0.01; ###: p < 0.001 compared to testosterone group; : p < 0.05; : p < 0.01; : p < 0.001 compared to rats treated only with plant extracts