Table 3 Effects of various treatments on body weight variation and relative organ weights of immature castrated rats after four weeks of treatment

Normal plus distilled water (10 ml/kg b.w.)

120.00 ± 6.4

173.40 ± 8.84

44.63 ± 1.94

232.78 ± 21.60

63.32 ± 5.05

41.37 ± 7.23

186.47 ± 30.51

Castrated plus distilled water (10 ml/kg b.w.)

124.8 ± 7.53

179 ± 14.89

43.17 ± 7.56

42.47 ± 5.94^C

16.06 ± 2.15^C

5.69 ± 0.54^C

10.00 ± 1.81^C

Castrated plus testosterone (0.5 mg/kg b.w.)

125.6 ± 3.41

207 ± 5.5

65.08 ± 4.69***

143.10 ± 2.67***

50.45 ± 3.52***

86.34 ± 2.93***

244.53 ± 23.11***

5% Tween 80 (10 ml/kg b.w.) + testosterone

120 ± 5.91

179.8 ± 15.16

49.15 ± 6.05**

141.15 ± 13.29***

51.36 ± 3.90***

68.83 ± 14.66***

243.75 ± 58.42***

Bicalutamide (2 mg/kg b.w.) + testosterone

127.4 ± 5.63

196.8 ± 15.39

54.30 ± 7.98

83.93 ± 7.98

38.30 ± 3.79^##

26.76 ± 0.82^###

112.54 ± 18.45^###

  100 mg/kg b.w.

120 ± 6.44

167 ± 5.89

39.73 ± 2.82

77.20 ± 5.00*

18.89 ± 0.91

10.35 ± 1.90

19.11 ± 2.24

  500 mg/kg b.w.

121 ± 8.28

161.8 ± 9.29

34.12 ± 1.90

61.76 ± 10.99

25.09 ± 3.72

11.06 ± 1.75

19.60 ± 3.77

  100 mg/kg b.w.

121.6 ± 5.9

174.6 ± 7.69

43.76 ± 2.20

38.62 ± 1.04

12.67 ± 0.39

6.74 ± 0.72

17.18 ± 1.87

  500 mg/kg b.w.

120.8 ± 1.61

169.8 ± 9.04

40.50 ± 0.75

40.18 ± 6.76

15.89 ± 2.18

8.074 ± 1.50

21.28 ± 4.49

  100 mg/kg b.w.

125.8 ± 5.06

184.6 ± 9.55

46.50 ± 2.93^###●

162.37 ± 8.60^●●●

54.85 ± 1.91^●●●

100.00 ± 8.43^●●●

322.15 ± 30.10^#●●●

  500 mg/kg b.w.

126.2 ± 3.93

187.4 ± 5.03

48.62 ± 1.91^###

165.86 ± 9.65^●●●

61.51 ± 4.03^#●●●

101.38 ± 2.66^●●●

325.08 ± 16.12^#●●●

  100 mg/kg b.w.

120.4 ± 5.91

175.6 ± 8.32

45.96 ± 2.39^###

182.87 ± 16.88^##●●●

72.86 ± 5.29^###●●●

162.15 ± 17.84^###●●●

544.91 ± 62.23^###●●●

  500 mg/kg b.w.

122 ± 4.51

185 ± 4.16

52.12 ± 3.95^≠

137.50 ± 8.16^●●●

65.16 ± 3.99^##●●●

146.33 ± 11.15^###●●●

455.53 ± 36.05^###●●●

  100 mg/kg b.w.

125.8 ± 5.79

183.8 ± 5.49

47.64 ± 5.67

79.35 ± 7.16

23.83 ± 2.64

6.315 ± 1.23

31.90 ± 4.28

  500 mg/kg b.w.

122.2 ± 5.3

183.4 ± 9.36

50.07 ± 1.99

34.74 ± 7.39

10.29 ± 2.64^●

1.31 ± 0.36

13.21 ± 1.85

  100 mg/kg b.w.

120.8 ± 4.89

161.6 ± 6.27

34.12 ± 4.71

33.34 ± 3.46

15.57 ± 1.90

4.79 ± 0.47

15.68 ± 2.34

  500 mg/kg b.w.

120 ± 5.97

167 ± 7.83

39.40 ± 3.63

43.35 ± 3.41

19.01 ± 0.67

7.63 ± 0.75

17.45 ± 1.93