Fig. 5

Effects of the compounds 3–5, 7 and 10 on the production of pro-inflammatory cytokines IL-1β (a) and IL-6 (b) in LPS-induced RAW264.7 macrophages. Cells were pre-treated for 2 h with indicated concentrations of 3–5, 7 and 10 and then stimulated with LPS (final concentration 1 μg/mL) for another 24 h. Data are expressed as mean ± S.D. Of three independent experiments. ## p < 0.01 as compared with the control group, * p < 0.05 and ** p < 0.01 versus the LPS group, △p < 0.05 and △△p < 0.01 versus the DXM group