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Table 5 Curative effect of S.guineense leaf extract against P. berghei infected mice

From: Antimalarial activity of Syzygium guineense during early and established Plasmodium infection in rodent models

Treatment Dose (mg/kg) Mean Parasitemia Survival time (days)
Pre –(D3) Post –(D7) Rx
Control (−ve) - 19 ± 0.62 43. ±0.76 7 ± 0.22
Extract 200 18 ± 0.63 17 ± 0.66 8 ± 0.72
400 17 ± 0.73 13 ± 0.72* 13 ± 0.14*
600 16 ± 0.81 6 ± 0.44* 15 ± 0.44*
Chloroquine 10 10 ± 0.83 2 ± 0.37* 28 ± 0.56*
  1. Values are expressed as means ± SEM, n = 5, * = significant at p < 0.05 compared to the negative control