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Table 5 Curative effect of S.guineense leaf extract against P. berghei infected mice

From: Antimalarial activity of Syzygium guineense during early and established Plasmodium infection in rodent models

Treatment Dose (mg/kg)

Mean Parasitemia

Survival time (days)

Pre –(D3)

Post –(D7) Rx

Control (−ve)

-

19 ± 0.62

43. ±0.76

7 ± 0.22

Extract

200

18 ± 0.63

17 ± 0.66

8 ± 0.72

400

17 ± 0.73

13 ± 0.72*

13 ± 0.14*

600

16 ± 0.81

6 ± 0.44*

15 ± 0.44*

Chloroquine

10

10 ± 0.83

2 ± 0.37*

28 ± 0.56*

  1. Values are expressed as means ± SEM, n = 5, * = significant at p < 0.05 compared to the negative control