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Table 4 Effect of S. guineense extract on survival time in the suppressive test

From: Antimalarial activity of Syzygium guineense during early and established Plasmodium infection in rodent models

Treatment

Group

Dose

Mean Survival times (days)

DW (negative control)

Group I

0.5 ml

7 ± 0.70

S. guineense leaf extract

Group II

200 mg/kg

8 ± 1.73ns

Group III

400 mg/kg

8.2 ± 1.30ns

Group IV

600 mg/kg

10.8 ± 2.59*

Chloroquine (standard)

Group V

10 mg/kg

28 ± 0.00*, **, ***, ****

  1. DW distilled water
  2. Values are expressed as means ± SEM, n = 5, ns = not significant, * = p < 0.05 compared to negative control, ** = p < 0.05 compared to 200 mg/kg, *** = p < 0.05 compared to 400 mg/kg, **** = p < 0.05 compared to 600 mg/kg of the extract