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Table 4 Effect of treatments on blood glucose, HbA1c, serum C-peptide, insulin, IL-6 and TNF−α

From: Hypoglycemic and pancreatic protective effects of Portulaca oleracea extract in alloxan induced diabetic rats

 

Group I

(Control)

Group II (PO-Control)

Group III

(Diabetic)

Group IV (PO-diabetic)

Blood Glucose

119.8 ± 1.0

109.0 ± 1.3

a293.2 ± 2.4

a,b125.0 ± 1.3

C peptide (ng/mL)

0.97 ± 0.03

1.00 ± 0.04

a,0.48 ± 0.02

b0.94 ± 0.02

Hb A1c (%)

4.99 ± 0.06

5.01 ± 0.07

a10.35 ± 0.12

a,b6.97 ± 0.02

Insulin (mIU/L)

35.50 ± 0.09

36.02 ± 0.08

a18.97 ± 0.09

b33.50 ± 0.08

TNFa (pg/ml)

34.90 ± 0.17

34.77 ± 0.21

a49.70 ± 0.55

b35.20 ± 0.24

IL- 6 (pg/ml)

15.02 ± 0.13

14.91 ± 0.12

a28.90 ± 0.34

b16.26 ± 0.17

  1. Values are presented as means ± SEM
  2. aValue significantly different vs. PO- control group or bfrom diabetic group, at P < 0.05