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Table 5 Formalin-induced paw-licking response of pure compounds

From: Sesquiterpene lactone! a promising antioxidant, anticancer and moderate antinociceptive agent from Artemisia macrocephala jacquem

Treatment/Dose

Licking time (Sec)

Inhibition (%)

1st Phase

2nd Phase

1st Phase

2nd Phase

Control (2% Tween 80)

51.85 ± 1.83

73.05 ± 1.75

----

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Morphine 5 mg

7.01 ± 1.153***

3.05 ± 1.290***

86.48

95.82

Indomethacin 10 mg

37.35 ± 1.37**

19.38 ± 1.440***

27.69

73.47

Ism-1 25 mg

50 mg

32.45 ± 1.231*

41.12 ± 1.204*

37.41

43.70

28.43 ± 1.356**

35.45 ± 1.198**

45.16

51.47

  1. All the values were expressed as mean ± SEM (n = 6). * P < 0.1, ** P < 0.01 and *** P < 0.001 when compared to control group (one way ANOVA followed by Dunnetts: compare all vs control test)
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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