Fig. 5

Effects of KDZ injection on changes of myocardial histomorphology of rats models of acute cerebral ischemia by H&E staining and hematoxylin-basic fuchsin picric (HBFP) staining (magnification: ×200). In the sham group, H&E staining showed that cardiomyocyte morphology was normal, myofibrils were orderly arranged, and myocardial cell gaps were uniform. In the 6h-ischemia group, myofibril arrangement was disorderly, myocardial cell gaps were widened, cracks had appeared, and edema was obvious. In the KDZ group, myocardial cell edema was decreased and gaps were smaller. Arrows: gaps. In the sham group, HBFP staining showed that myocardial fibers were golden and the nuclei were blue. In the 6h-ischemia group, myocardial fibers were red and arranged in large sheets with diffuse distribution and dark red staining. In the KDZ group, compared with the model group, red staining of myocardium fiberswas weaker, with a smaller number, and more dispersed