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Table 3 Part of the enrichment data of target proteins of Radix Morindae officinalis

From: Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging

Biological process

P value

Ratio

Involved targets

response to chemical stimulus

7.95E-15

0.61

TNF, CCL2, PTGS2, TNC, TH, MME, TGFB1, VCAM1, and other 5 targets

response to stress

8.55E-13

0.61

TNF, CCL2, PTGS2, TNC, TH, MME, TGFB1, SLC11A2, and other 12 targets

response to stimulus

1.66E-11

0.77

TNF, CCL2, PTGS2, TNC, TH, MME, TGFB1, VCAM1, and other 6 targets

response to inorganic substance

1.66E-11

0.29

CUTA, PTGS2, CYP1A1, OLR1, RELA, TNC, SOD1, SOD3, and other 11 targets.

response to wounding

4.25E-10

0.35

IL6, TNF, CCL2, OLR1, CYP1A1, RELA, TNC, MME, and other 9 targets

regulation of immune system process

1.90E-09

0.31

ICAM1, IL6, TNF, CCL2, RELA, SOD1, TGFB1, VCAM1, and other 7 targets

response to drug

1.19E-08

0.24

CCL2, TNF, CYP1A1, PTGS2, JUN, RELA, MME, IL1B, and other 13 targets

positive regulation of response to stimulus

1.77E-08

0.24

IL6, CCL2, TNF, PTGER3, PTGS2, CD40LG, RELA, and other 17 targets