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Table 1 Some collected sample data of herbal medicines

From: Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging

Herbal names (Latin)

Hepatorenal toxicity

Effect

Molecular ingredients (CAS number)

Targets

Ba ji tian (Radix Morindae officinalis)

None

tonifying kidney-Yang

Aascorbic acid (CAS:1972-08-3)

PTGER3, TGFA, VEGFA, FTMT, SLC11A2, and other 42 targets

Ci wu jia (Radix seu Caulis et Folium Acanthopana)

None

tonifying kidney-Yang

Sesamin (CAS:607-80-7)

NOS3, NOX1, UGT1A1, CYP2B6, CCND1, and other 12 targets

Du zhong (Cortex Eucommiae)

None

tonifying kidney-Yang

Aucubin (CAS:479-98-1)

BCL2, BAX, TNF, IL6, RELA, NFKBIA, and other 27 targets

Bu gu zhi (Fructus Psoraleae)

long-term risks of causing kidney disease

tonifying kidney-Yang

Angelicin (CAS:523-50-2)

CYP1A1, ESR1, ESR2, ESTRB, NR3A2, and other 27 targets

Di huang (Radix Rehmanniae)

None

tonifying kidney-Yin

Catalpol (CAS:2415-24-9)

NOS2, SOD1, CASP3, BCL2, ICAM1, and other 14 targets

Nv zhen (Radix Ligustri lucidi)

None

tonifying kidney-Yin

Ursolic acid (CAS:77-52-1)

JUN, PTGS2, ACHE, MMP9, RELA, and other 39 targets

Sang shen (Fructus Mori)

None

tonifying kidney-Yin

Morin (CAS:480-16-0)

XDH, PIP4K2A, ALOX5, CD36, BATF3, and other 58 targets

Gou qi zi (Fructus Lycii)

None

tonifying kidney-Yin

Beta-carotene (CAS:7235-40-7)

CYP3A4, Cyp2b1, CYP1A2, HMOX1, ALB, and other 77 targets