Fig. 4From: Activation of hippocampal MEK1 contributes to the cumulative antinociceptive effect of electroacupuncture in neuropathic pain ratsEffect of intra-hippocampal microinjection of the selective MEK1 inhibitor PD98059 at different time-points on PWL in a rat model of neuropathic pain. a Microinjection was given on the first 3 days of EA, b microinjection was given from the 8th day of EA. The black arrowheads indicate the day of PD98059 or DMSO administration. Data are presented as the mean ± SD; n = 10 in each group. #P < 0.05 vs. CCI+ PD98059 + EA groupBack to article page