Table 2 Cytotoxicity (LC50 in μg/mL) of compounds 1–3 and their selectivity index (SI)
Compounds | Cytotoxicty (LC50) | Selectivity Index* | |||||||
|---|---|---|---|---|---|---|---|---|---|
HeLa cells | Vero cells | HeLa cells | V. cholerae SG24 | V. cholerae CO6 | V. cholerae NB2 | V. cholerae PC2 | S. flexneri SDINT | S. aureus ATCC 25923 | |
1 | 8.18 ± 0.92a | 93.02 ± 2.54a | 11.37 | / | 0.18 | 0.18 | / | 0.72 | 0.72 |
2 | 35.69 ± 1.31b | 129.10 ± 1.20b | 3.61 | / | 0.25 | 0.25 | 0.50 | 1.00 | 0.50 |
3 | 3.66 ± 0.33c | 73.88 ± 0.92c | 20.18 | / | 0.14 | 0.14 | / | 0.57 | 0.14 |
5-FU | 0.25 ± 0.05d | 4.63 ± 0.17d | 18.52 | / | / | / | / | / | / |