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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Evaluation of anti-tumorigenic activity of BP3B against colon cancer with patient-derived tumor xenograft model

Fig. 3

Induction of tumor apoptosis by BP3B in PDTX model. a To measure the apoptotic tissues in BP3B-treated tumors, TUNEL assay was performed. Apoptotic cells were visualized into green and nuclei were stained with DAPI (blue). The intensity of image was calculated with ImmunoRatio software. Scale bars are 50 μm. ** p < 0.01 and *** p < 0.001. b Expression pattern of apoptosis-related proteins (PARP and Cleaved-caspase3) was confirmed with western blot after lysis of tumor tissues. Densitometric analysis was performed with Image J software

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