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Table 8 Effect of F. olivieri on liver marker enzymes in acetaminophen induced toxicity in rats

From: Hepatoprotective potential of Fagonia olivieri DC. against acetaminophen induced toxicity in rat

Treatment mg/kg bw AST (U/l) ALT (U/l) ALP (U/l) LDH (U/l) Total bilirubin (mg/dl)
Control (Saline) 31.90 ± 2.31d 25.93 ± 5.11d 158.65 ± 3.00d 53.21 ± 1.46d 1.18 ± 0.17c
AMP 750 71.49 ± 2.98a 67.99 ± 3.01a 325.11 ± 2.80a 86.52 ± 1.58a 2.16 ± 0.64a
AMP + Sily 50 63.24 ± 1.23b 54.87 ± 2.67a 231.42 ± 2.12b 59.38 ± 1.34c 2.08 ± 0.12a
AMP + FOM 200 53.71 ± 2.09b 46.78 ± 1.76b 187.64 ± 2.45c 71.69 ± 2.03b 1.82 ± 0.45b
AMP + FOM 400 44.39 ± 2.31c 38.75 ± 2.45c 146.73 ± 1.91d 56.03 ± 1.32c 1.29 ± 0.58c
FOM 400 35.30 ± 1.22d 27.33 ± 0.91d 142.19 ± 2.28d 51.84 ± 1.11d 1.25 ± 0.13c
  1. Mean ± SEM (06). Means with different superscript letters (a-d) within the column indicate significant difference (p <0.05). AMP, acetaminophen; FOM, F. olivieri methanol extract