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Table 10 Effect of FOM on antioxidant enzyme activities in acetaminophen induced hepatotoxicity in rats

From: Hepatoprotective potential of Fagonia olivieri DC. against acetaminophen induced toxicity in rat

Treatment (mg/kg bw) Catalase (U/mg protein) SOD (U/mg protein) GSH-Px (nM/min/mg protein) GR (nM/min/mg protein)
Control (Saline) 5.85 ± 0.13c 4.23 ± 0.22d 114.75 ± 0.97c 127.53 ± 1.90d
AMP 750 2.44 ± 0.04a 1.18 ± 0.25a 69.82 ± 0.20a 75.82 ± 1.65a
AMP + Sily 50 5.68 ± 0.21c 4.32 ± 0.12d 116.14 ± 0.31c 125.31 ± 2.29c
AMP + FOM 200 3.95 ± 0.02b 2.82 ± 0.10b 81.52 ± 1.25b 97.25 ± 1.85b
AMP + FOM 400 5.71 ± 0.15c 3.78 ± 0.57c 110.59 ± 2.18c 116.84 ± 1.39c
FOM 400 5.89 ± 0.43c 4.27 ± 0.49d 118.72 ± 0.66c 129.58 ± 1.75d
  1. Mean ± SEM (06). Means with different superscript letters (a-d) within the column indicate significant difference (p <0.05). AMP, acetaminophen; FOM, F. olivieri methanol extract