Table 5 Effects of the aqueous extract of V. heterophylla on the serum parameters
Drugs (mg/kg) | glucose (mg/dl) | Creatinine (mg/dl) | Urea (mg/dl) | Albumin (g/l) | Aldosterone (pg/mL) | Na+ (méq.L–1) | K+ (méq.L–1) | POSM (mosmol/kg) | |
|---|---|---|---|---|---|---|---|---|---|
Control | 89,22 ± 2,11 | 0,55 ± 0,22 | 21,12 ± 0,38 | 42,52 ± 1,14 | 279,34 ± 13,41 | 1,76 ± 0,43 | 1,80 ± 0,77 | 269,11 ± 11,11 | |
Extract | 150 | 90,45 ± 2,34* | 0,62 ± 0,45* | 22,38 ± 1,11 | 43,66 ± 1,22 | 281,22 ± 21,55 | 6,42 ± 0,75*** | 3,79 ± 1,66*** | 277,52 ± 12,33** |
200 | 91,66 ± 4,33* | 0,66 ± 0,57** | 23,89 ± 2,44** | 44,72 ± 2,34** | 287,57 ± 12,12** | 8,22 ± 1,56*** | 4,78 ± 2,52*** | 279,66 ± 21,42*** | |
250 | 95,88 ± 3,41* | 0,87 ± 0,29*** | 26,77 ± 2,33*** | 44,65 ± 3,67*** | 306,11 ± 32,22*** | 10,88 ± 1,56*** | 5,74 ± 1,16*** | 285,33 ± 23,43*** | |
Furosemide (5 mg/kg) | 95,67 ± 4,98* | 0,75 ± 0,23*** | 24,56 ± 3,33** | 44,43 ± 1,63** | 302,53 ± 23,35*** | 11,22 ± 1,42*** | 6,73 ± 1,34*** | 284,21 ± 24,14*** | |
HCTZ (10 mg/kg) | 94,22 ± 3,55* | 0,74 ± 0,61*** | 26,22 ± 1,13*** | 43,66 ± 1,32*** | 292,88 ± 11,23*** | 7,31 ± 1,72*** | 9,89 ± 2,51*** | 286,44 ± 31,56*** | |