Fig. 1

Overload eliminated and urination latency. Overload eliminated after 1 h and latency to first urination by rats treated with the three highest doses of V. heterophylla aqueous extract tested, administered with an equivalent volume of distilled water (negative controls), or rats treated with one of the two diuretic drugs used as positive controls. Note that all treatments induced at least a 3-fold increase in the overload elimination compared with negative controls. ANOVA + LSD test against negative control group: *P < 0.05, **P < 0.01, ***P < 0.001