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Table 2 Dietary intakes of energy and nutrients in treatment groups before and after intervention

From: The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and anthropometric features in patients with Hashimoto’s thyroiditis: a randomized controlled trial

N Nigella sativa Placebo P
N = 20 N = 20
Total calories (kcal/d)
 Before 2251.90 ± 349.58 2208.95 ± 327.80 0.69
 After 2236.40 ± 248.27 2265.45 ± 270.73 0.72
P 0.77 0.32  
Carbohydrate (%)
 Before 57.11 ± 2.90 57.07 ± 3.78 0.97
 After 57.24 ± 2.71 57.58 ± 3.32 0.72
P 0.26 0.67  
Protein (%)
 Before 15.73 ± 1.68 15.07 ± 1.29 0.17
 After 15.77 ± 1.36 15.10 ± 1.81 0.19
P 0.94 0.94  
Fat (%)
 Before 27.34 ± 2.15 26.57 ± 2.32 0.28
 After 26.56 ± 1.96 26.13 ± 2.48 0.55
P 0.51 0.51  
Vitamin E (mg/d)
 Before 2.98 ± 1.08 3.43 ± 1.48 0.36
 After 2.89 ± 1.64 3.40 ± 1.19 0.28
P 0.80 0.96  
Vitamin C (mg/d)
 Before 79.75 ± 22.69 75.67 ± 17.24 0.52
 After 28.37 ± 11.84 75.45 ± 15.36 0.59
P 0.77 0.91  
  1. Data are presented as mean ± SD, †P values for ANOCOVA after adjustment for age, gender, duration of the disease and variable’s baseline value; ‡P values for paired t-test