The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Table 2 Effect of treating CCl₄ induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on the weekly water consumption

Water consumed ml/day	Statistics	G1	G2	G3	G4
Water consumed ml/day	Statistics	N. Control	P. Control	Olive oil	N. sativa oil
1st week	Mean ± SE	33.33 ± 1.05 ab	32.50 ± 1.11 b	36.33 ± 0.88 a	36.33 ± 0.88 a
	LSD 0.05 = 3.257	33.33 ± 1.05 ab	32.50 ± 1.11 b	36.33 ± 0.88 a	36.33 ± 0.88 a
	T-test	-	0.41 NS	−4.60***	−2.49*
2nd week	Mean ± SE	33.66 ± 0.88 b	32.50 ± 1.11 b	34.83 ± 0.90 b	37.16 ± 0.79 a
	LSD 0.05 = 2.308	33.66 ± 0.88 b	32.50 ± 1.11 b	34.83 ± 0.90 b	37.16 ± 0.79 a
	T-test	-	1.40 NS	−1.68 NS	−3.97**
3rd week	Mean ± SE	27.50 ± 1.11 b	38.00 ± 0.96 a	28.00 ± 1.00 b	29.16 ± 1.53 b
	LSD 0.05 = 3.766	27.50 ± 1.11 b	38.00 ± 0.96 a	28.00 ± 1.00 b	29.16 ± 1.53 b
	T-test	-	−11.38***	5.59***	6.30***
4th week	Mean ± SE	27.50 ± 1.11a	32.00 ± 1.00 ab	30.00 ± 1.29 b	29.00 ± 2.08 b
	LSD 0.05 = 3.235	27.50 ± 1.11a	32.00 ± 1.00 ab	30.00 ± 1.29 b	29.00 ± 2.08 b
	T-test	-	−2.18*	1.22 NS	1.04 NS

Data are represented as mean ± SE. T-test values ^*: significant at P < 0.05,^**: significant at P < 0.01, ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P> 0.05. LSD least significant difference, N.S non significant

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