The hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats

Table 1 Effect of treating CCl₄ induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on food intake

Food Intake g/day	Statistics	G1	G2	G3	G4
Food Intake g/day	Statistics	N. Control	P. Control	Olive oil	N. sativa oil
1st week	Mean ± SE	14.50 ± 0.22 ^a	14.50 ± 0.223 ^a	14.66 ± 0.21 ^a	14.50 ± 0.23 ^a
	LSD 0.05 = 0.719	14.50 ± 0.22 ^a	14.50 ± 0.223 ^a	14.66 ± 0.21 ^a	14.50 ± 0.23 ^a
	T-test	-	0.00^NS	−0.41^NS	0.01^NS
2nd week	Mean ± SE	16.16 ± 0.16 ^a	15.83 ± 0.16 ^a	15.50 ± 0.22 ^a	15.50 ± 0.22 ^a
	LSD 0.05 = 0.730	16.16 ± 0.16 ^a	15.83 ± 0.16 ^a	15.50 ± 0.22 ^a	15.50 ± 0.22 ^a
	T-test	-	1.58 ^NS	1.58 ^NS	1.58 ^NS
3rd week	Mean ± SE	19.16 ± 0.54 ^a	18.16 ± 0.40 ^ab	17.00 ± 0.44^b	17.16 ± 0.40 ^b
	LSD 0.05 = 1.128	19.16 ± 0.54 ^a	18.16 ± 0.40 ^ab	17.00 ± 0.44^b	17.16 ± 0.40 ^b
	T-test	-	3.87^**	2.90^*	2.23^*
4th week	Mean ± SE	20.01 ± 0.00 ^a	20.00 ± 0.00 ^a	20.02 ± 0.00 ^a	20.03 ± 0.00 ^a
	LSD 0.05 = 0.251	20.01 ± 0.00 ^a	20.00 ± 0.00 ^a	20.02 ± 0.00 ^a	20.03 ± 0.00 ^a
	T-test	-	0.00 ^NS	0.02^NS	0.01^NS

Data are represented as mean ± SE. T-test values ^*: significant at P < 0.05,^**: significant at P < 0.01. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P> 0.05. LSD least significant difference, N.S non significant

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