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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Treatment of allergic rhinitis with acupoint herbal plaster: an oligonucleotide chip analysis

Fig. 2

a Volcano plot of the 1852 filtered genes and b functional and clustering analyses of the differentially expressed genes between Ph-positive and -negative groups. a In the volcano plot, the -log10(P value) is plotted on the y-axis, and the log2 ratio of the fold change is plotted on the x-axis. In total, 89 genes (red points) that exhibited fold-changes exceeding 20.75 = 1.682 between Ph-positive and -negative groups were selected from the 1852 filtered genes (p < 0.01, Student’s t-test). b The 89 differentially expressed genes were analyzed with MetaCore software, and “Immune response_IL-13 signaling via JAK-STAT” and “Inflammation_Interferon signaling” pathways were found to correspond to up- and down-regulated genes, respectively, in Ph-positive patients. The genes involved in pathway are indicated with arrows

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