Fig. 5

PSR post-treatment reduces neurological deficit and cerebral infarct in MCAO rats. a Rats were post-treated with vehicle (con) or different doses of PSR, and neurological scores were determined 24, 48, and 72 h after MCAO. Infarct area (b), infarct volume (c), edema content (d) were measured 72 h after MCAO. e Adult rats were post-treated with vehicle (con) or PSR 1.1 g/kg for up to 28 d after MCAO. Neurological scores measured at 7, 14, 21, and 28 d after MCAO are shown. For (a-c), the numbers of animals in the control, PSR 1.1, 2.2 and 5.5 g/kg groups were 17, 9, 12 and 9, respectively. For (d), n for control = 13. For (e), the numbers of animals for control and PSR 1.1 g/kg groups at day 7, 14, 21 and 28 were 17, 17, 9, 8 and 16, 14, 9, 8, respectively. In (a, b) and (e), statistical significance between PSR-treated and control groups was analyzed by two-way ANOVA followed by Bonferroni post-test, respectively. In (c-d), statistical significance between PSR-treated and control groups was analyzed by one-way ANOVA followed by Newman-Keuls post-test