Table 4 Effect of FXM on comet parameters of liver cells in rat

Control

33.26 ± 1.17^d

26.55 ± 1.14^c

6.71 ± 1.85^d

96.81 ± 0.94^a

3.18 ± 0.94^d

0.51 ± 0.02^c

DMSO + Olive oil

33.16 ± 1.03^d

26.27 ± 0.36^c

6.88 ± 1.29^d

96.89 ± 1.00^a

3.10 ± 1.00^d

0.52 ± 0.01^c

CCl₄

65.21 ± 1.74^ǂa

42.01 ± 2.02^ǂa

23.20 ± 2.56^ǂa

70.00 ± 1.54^ǂd

29.99 ± 1.54^ǂa

1.80 ± 0.10^ǂa

CCl₄ + silymarin (100 mg/kg)

40.79 ± 1.67^ǂc

28.71 ± 1.01^*c

12.07 ± 1.56^ǂbc

89.81 ± 1.13^ǂb

10.18 ± 1.13^ǂc

0.60 ± 0.03^≠bc

CCl₄ + FXM (200 mg/kg)

49.25 ± 2.32^ǂb

33.29 ± 1.19^ǂb

15.96 ± 3.25^ǂb

85.86 ± 1.68^ǂc

14.14 ± 1.68^ǂb

0.68 ± 0.02^ǂb

CCl₄ + FXM (400 mg/kg)

40.98 ± 1.68^ǂc

26.86 ± 1.08^c

14.11 ± 1.56^ǂb

90.65 ± 1.32^ǂb

9.35 ± 1.32^ǂc

0.60 ± 0.02^≠bc

FXM (200 mg/kg)

33.93 ± 1.60^d

26.22 ± 0.99^c

7.71 ± 2.44^cd

94.74 ± 2.23^a

5.25 ± 2.23^d

0.53 ± 0.01^c

FXM (400 mg/kg)

34.32 ± 1.33^d

26.43 ± 1.41^c

7.88 ± 1.60^cd

95.37 ± 1.03^a

4.62 ± 1.03^d

0.53 ± 0.01^c