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Table 2 Effect of EP extract/fraction on copper - 1, 10 - phenanthroline dependent DNA damage

From: Pro-apoptotic and cytotoxic effects of enriched fraction of Elytranthe parasitica (L.) Danser against HepG2 Hepatocellular carcinoma

Concentration (μg/mL)

Extent of DNA damage (A530nm)

Test compounds

EP.M

EP.PE

EP.DEE

EP.EA

EP.But

EP.Aq

Ascorbic acid

10

0.04 ± 0.001

0.04 ± 0.008

0.04 ± 0.004

0.04 ± 0.002

0.04 ± 0.004

0.03 ± 0.004

0.08 ± 0.004

100

0.06 ± 0.005

0.04 ± 0.004

0.07 ± 0.004

0.04 ± 0.001

0.04 ± 0.002

0.07 ± 0.002

0.10 ± 0.009

500

0.12 ± 0.001

0.04 ± 0.007

0.08 ± 0.002

0.13 ± 0.002

0.13 ± 0.004

0.05 ± .0.001

0.18 ± 0.007

1000

0.22 ± 0.002

0.11 ± 0.001

0.10 ± 0.002

0.18 ± 0.003

0.17 ± 0.008

0.04 ± 0.001

0.30 ± 0.007

Control

0.06 ± 0.003

  1. Values are expressed as mean ± SEM (of three observations). EP.M Methanol extract, EP.PE Petroleum ether fraction, EP.DEE Diethyl ether fraction, EP.EA Ethyl Acetate fraction, EP.But Butanol fraction, EP.Aq Aqueous fraction