Antinociceptive effect of methanol extract of Celosia cristata Linn. in mice

Table 2 Effect of oral administration of MECC on gross changes to the vital organs of mice

Treatment	Organ weight (g) (Organ body index in %)
Treatment	Body weight	Heart	Kidneys	Liver	Lungs	Spleen
Vehicle	22.04 ± 0.25	0.15 ± 0.01 (0.66)	0.38 ± 0.01 (1.72)	1.32 ± 0.02 (6.01)	0.23 ± 0.02 (1.03)	0.10 ± 0.01 (0.46)
MECC (1000 mg/kg)	21.28 ± 0.16	0..11 ± 0.01 (0.52)	0.32 ± 0.02 (1.48)	1.33 ± 0.13 (6.23)	0.18 ± 0.01 (0.86)	0.07 ± 0.01 (0.35)
MECC (2000 mg/kg)	23.39 ± 0.48	0.18 ± 0.01 (0.79)	0.44 ± 0.03 (1.85)	1.79 ± 0.12 (7.78)	0.27 ± 0.02 (1.14)	0.15 ± 0.02 (0.63)
MECC (4000 mg/kg)	23.27 ± 0.58	0.17 ± 0.01 (0.89)	0.41 ± 0.03 (1.74)	1.76 ± 0.19 (7.52)	0.29 ± 0.04 (1.23)	0.14 ± 0.02 (0.60)

Each value is presented as the mean ± SEM (n = 5). MECC = Methanol extract of C. cristata, organ body index (%) = (weight of organ/weight of body)/100. P is not ≤ 0.05, compared to control group (Dunnett’s test)

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