Fig. 5

Effect of GR on COX-2 and PGE₂ abundance in DSS-induced colitis. Ulcerative colitis was induced and GR and 5-ASA administered as described in the legend to Fig. 1. COX-2 levels were determined by Western blot analysis, and PGE₂ levels using PGE₂ assay kits. a Western blot analysis was used to determine COX-2 levels in colonic tissues. Data shown are representative of three independent experiments. b COX-2/GAPDH ratios were determined by densitometry. c PGE₂ production in colonic tissues. Values represent mean ± S.E.M. (\( n \) = 6). Data were analyzed by Tukey post hoc test (^# P < 0.05 versus control and ^* P < 0.05 versus DSS alone)