Fig. 3

Effect of GR on levels of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-\( \alpha \)) in DSS-induced colitis. Ulcerative colitis was induced and GR and 5-ASA administered as described in the legend to Fig. 1. Cytokine production was determined by ELISA. a IL-6 production in mouse serum at day 10. b TNF-α production in mouse serum at day 10. c IL-6 production in colon tissue. d TNF-α production in colon tissue. Values represent mean ± S.E.M. (\( n \) = 6). Data were analyzed by Tukey post hoc test (^# \( P \) < 0.05 versus control and ^* \( P \) < 0.05 versus DSS alone)