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Table 2 The effects of DFE, DPE and coffee on comet DNA assay parameters in CCl4-intoxicated rats. Values are expressed as mean ± SEM

From: The antifibrotic and fibrolytic properties of date fruit extract via modulation of genotoxicity, tissue-inhibitor of metalloproteinases and nuclear factor- kappa B pathway in a rat model of hepatotoxicity

 

Tailed DNA

(%)

Tail length

(μm)

Tail intensity

(%)

Tail moment

(Unit)

Control

4.25 ± 0.31

1.67 ± 0.045

2.56 ± 0.046

4.75 ± 0.161

CCl4

9.25a*** ± 0.44

3.25 a*** ± 0.1

3.7 a*** ± 0.068

11.74 a*** ± 0.324

DFE+ CCl4

6.83 b** ± 0.31

2.48 b*** ± 0.11

2.87 b*** ± 0.038

7.84 b*** ± 0.24

DPE+ CCl4

6.84 b** ± 0.477

2.83 b*c* ± 0.08

2.83 b*** ± 0.057

9.12 b**c** ± 0.084

Coffee + CCl4

7.25 b** ± 0.362

2.64 b** ± 0.176

2.73 b*** ± 0.042

8.43 b*** ± 0.22

  1. ***P < 0.001, **P < 0.01, *P < 0.05
  2. asignificantly different from normal control group; bsignificantly different from CCl4-treated group; csignificantly different from DFE-treated group